Send to:

Choose Destination
See comment in PubMed Commons below
Arch Otolaryngol Head Neck Surg. 1996 Nov;122(11):1169-73.

Combined use of superpulsed carbon dioxide laser and cryotherapy for treatment of facial rhytids.

Author information

  • 1Division of Otolaryngology-Head and Neck Surgery, Stanford University Medical Center, Calif, USA.

Erratum in

  • Arch Otolaryngol Head Neck Surg 1997 Jan;123(1):46.



To compare the effect of superpulsed carbon dioxide (CO2) laser alone with that of cryotherapy in combination with CO2 laser in treatment of facial rhytids.


A randomized prospective study.


Facial Plastic Surgery Clinic at Standford University Medical Center, Standford, Calif.


Twenty patients with perioral rhytids were randomized in the study, 11 in the laser group and 9 in the cryotherapy and laser group.


Patients in the laser group were treated with superpulsed CO2 laser. Initially, the shoulders of rhytids were spot treated. The area was then wiped and rehydrated. The entire surface was then treated with a second pass. A third pass, if deemed necessary, was then used to treat the shoulders. Patients in the combined group underwent cryotherapy of the entire perioral region followed by CO2 laser treatment similar to that previously described.


Improvement in facial rhytids with laser treatment alone was compared with improvement using cryotherapy and laser. A skin wrinkle grading system was used and patients were graded by 3 independent observers. Close-up photographs were obtained preoperatively and postoperatively. A questionnaire was filled out by each patient 1 month following treatment and was used to rate overall patient satisfaction.


There was no statistically significant difference between the 2 groups regarding final outcome, amount of anesthetic agents required for each patient, or rate of complications.


Superpulsed CO2 skin resurfacing alone is as effective as combined cryotherapy and superpulsed CO2 laser for treatment of perioral rhytids.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Write to the Help Desk