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Brain Dev. 1996 Sep-Oct;18(5):376-8.

Early communication development in children with Rett syndrome.

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  • 1Department of Speech Pathology and Audiology, University of Alberta, Edmonton, Canada.


This retrospective pilot study investigated the course of pre-linguistic and linguistic communication development in children with Rett syndrome (RS) from birth to 24 months of age. Parents of 17 children with RS completed a questionnaire based on the Clinical Linguistic Auditory Milestone Scale. No child exceeded single word use and most children had begun to regress. Pre-regression delay was in evidence along with limited intentional gestural communication as a precursor to single word use. Limited use of communicative gestures is suggested as a possible early predictor of RS pending further investigation.

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