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J Hypertens. 1996 Aug;14(8):1005-10.

Echocardiography overestimates left ventricular mass: a comparative study with magnetic resonance imaging in patients with hypertension.

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  • 1Department of Medicine, St George's Hospital Medical School, London, UK.

Abstract

OBJECTIVE:

To compare measurement of left ventricular mass (LVM) by M-mode echocardiography and magnetic resonance imaging (MRI) in hypertensive subjects.

DESIGN:

A prospective study.

SUBJECTS:

Twenty-four untreated hypertensive patients [19 men and five women, aged 51 +/- 2 (mean +/- SEM) years, supine blood pressure 159/101 +/- 3/1 mmHg].

SETTING:

The Blood Pressure Unit, St Georges Hospital Medical School and Magnetic Resonance Unit, Royal Brompton National Heart and Lung Hospital, London.

MAIN OUTCOME MEASURES:

LVM estimated both by M-mode echocardiography and by MRI.

RESULTS:

Using three standard M-mode formulae, widely different values of LVM were obtained with echocardiography [American Society of Echocardiography (ASE) 319 +/- 21 g, Penn 273 +/- 19 g. Teichholz 191 +/- 11 g]. By MRI, the LVM was 232 +/- 11 g. The differences between MRI and echocardiography could not be explained in terms of the timing of measurements in the cardiac cycle. When single-slice MRI measurements at the appropriate level were applied to the ASE and Penn formulae, the LVM was again overestimated.

CONCLUSION:

Our study has shown major differences in LVM estimated using methods based on one-dimensional (echocardiography) compared with three-dimensional (MRI) data. These differences seem to be largely the result of the geometrical assumptions on which M-mode measurements are based. Our findings have important clinical implications for the assessment of the severity and response to treatment of left ventricular hypertrophy in hypertensive patients.

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PMID:
8884556
[PubMed - indexed for MEDLINE]
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