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Mapping of unconventional myosins in mouse and human.
Hasson T,
Skowron JF,
Gilbert DJ,
Avraham KB,
Perry WL,
Bement WM,
Anderson BL,
Sherr EH,
Chen ZY,
Greene LA,
Ward DC,
Corey DP,
Mooseker MS,
Copeland NG,
Jenkins NA.
Department of Biology, Yale University, New Haven, Connecticut 06520, USA.
Myosins are molecular motors that move along filamentous actin. Seven classes of myosin are expressed in vertebrates: conventional myosin, or myosin-II, as well as the 6 unconventional myosin classes-I, -V, -VI, -VII, -IX, and -X. We have mapped in mouse 22 probes encompassing all known unconventional myosins and, as a result, have identified 16 potential unconventional myosin genes. These genes include 7 myosins-I, 2 myosins-V, 1 myosin-VI, 3 myosins-VII, 2 myosins-IX, and 1 myosin-X. The map location of 5 of these genes was identified in human chromosomes by fluorescence in situ hybridization.
PMID: 8884266 [PubMed - indexed for MEDLINE]
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