Med J Aust. 1977 Jun 18;1(25):923-7.

Cystic fibrosis screening by sweat analysis: a critical review of techniques.

Abstract

Currently employed methods for the assay of electrolytes in sweat, relevant to the diagnosis of cystic fibrosis, are critically evaluated with particular reference to the measurement of electrical conductivity. Attention is drawn to the factors responsible for potentially large errors. On the basis of experimentation, supported by laboratory practice, recommendations are made for the reduction of these errors to clinically acceptable levels. Data concerning sodium and potassium content, electrical conductivity and osmolality of undiluted sweat collections are compared. The feasibility and comparative advantages of measuring sweat osmolality with a vapour pressure osmometer are discussed.

PMID:: 887027; [PubMed - indexed for MEDLINE]

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Improved sweat test method for the diagnosis of cystic fibrosis. [Arch Dis Child. 1984]
Improved sweat test method for the diagnosis of cystic fibrosis.
Carter EP, Barrett AD, Heeley AF, Kuzemko JA. Arch Dis Child. 1984 Oct; 59(10):919-22.
Measurement of osmolality and sodium concentration in heated-cup sweat collections for the investigation of cystic fibrosis. [Ann Clin Biochem. 1983]
Measurement of osmolality and sodium concentration in heated-cup sweat collections for the investigation of cystic fibrosis.
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Review [Methods of electrolyte determination in sweat for diagnosis of mucoviscidosis]. [Kinderarztl Prax. 1978]
Review [Methods of electrolyte determination in sweat for diagnosis of mucoviscidosis].
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Cited by 2 PubMed Central articles

Osmosis, osmometry, and osmoregulation. [Postgrad Med J. 1999]
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Sweat osmolality in Down's syndrome and cystic fibrosis in an Indian population. [Br Med J (Clin Res Ed). 1987]
Sweat osmolality in Down's syndrome and cystic fibrosis in an Indian population.
Geetha H, Shetty KT. Br Med J (Clin Res Ed). 1987 Jan 17; 294(6565):156.

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