Foot Ankle Int. 1996 Aug;17(8):496-8.

Partial Achilles tendon ruptures associated with fluoroquinolone antibiotics: a case report and literature review.

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Department of Orthopaedic Surgery, Baylor College of Medicine, Houston, Texas, USA.

Abstract

Fluoroquinolone antibiotics (such as olprofloxacin, pefloxacin, ofloxacin, norfloxacin, temafloxacin, etc.) have recently been implicated in the etiology of Achilles tendinitis and subsequent tendon rupture. We report on a patient with bilateral partial Achilles tendon ruptures associated with ciprofloxacin therapy and present a review of the current literature on this increasingly recognized complication. Treatment with fluoroquinolones should be discontinued at the first sign of tendon inflammation so as to reduce the risk of subsequent rupture. Magnetic resonance imaging is useful in distinguishing between Achilles tendinitis and partial tendon rupture.

PMID:: 8863030; [PubMed - indexed for MEDLINE]

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Cited by 3 PubMed Central articles

The Risk of Fluoroquinolone-induced Tendinopathy and Tendon Rupture: What Does The Clinician Need To Know? [J Clin Aesthet Dermatol. 2010]
The Risk of Fluoroquinolone-induced Tendinopathy and Tendon Rupture: What Does The Clinician Need To Know?
Kim GK. J Clin Aesthet Dermatol. 2010 Apr; 3(4):49-54.
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Fluoroquinolone and fortified antibiotics for treating bacterial corneal ulcers. [Br J Ophthalmol. 2000]
Fluoroquinolone and fortified antibiotics for treating bacterial corneal ulcers.
Gangopadhyay N, Daniell M, Weih L, Taylor HR. Br J Ophthalmol. 2000 Apr; 84(4):378-84.

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