Your browser version may not work well with NCBI's Web applications. More information here...
1: Prog Neuropsychopharmacol Biol Psychiatry. 1996 Jan;20(1):121-7.Click here to read Links

Chronic nimodipine and yawning behavior in grouped or individually housed rats.

Fundaro A.

Institute of Pharmacology and Pharmacognosy, School of Pharmacy, University of Turin, Italy.

1. The effects of a chronic administration (around 30 mg/ kg/day) of the dihydropyridine calcium antagonist nimodipine, on apomorphine induced yawning behaviour of grouped or individual housed rats, were studied. 2. Nimodipine treatment had no effect in grouped rats. 3. Individually housed animals gave a significant lower number of yawns in respect to grouped controls: this difference disappeared in isolated, nimodipine treated, group. 4. The results show the ability of nimodipine to restore a depressed behavioural performance.

PMID: 8861182 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Apomorphine (Apokyn® )

    Apomorphine is used to treat ''off'' episodes (times of difficulty moving, walking, and speaking that may happen as medication wears off or at random) in patients with Parkinson's disease (PD; a disorder of the nervous s...

  • Nimodipine (Nimotop® )

    Nimodipine is used to treat symptoms resulting from a ruptured blood vessel in the brain (hemorrhage). It increases blood flow to injured brain tissue.

  • Source: AHFS Consumer Medication Information