Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Dev Dyn. 1996 Mar;205(3):293-307.

Quantitative analysis of proliferation and cell cycle length during development of the rat retina.

Author information

  • 1Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.


The rat retina has been a useful model system for the study of the development of the central nervous system (CNS). In order to facilitate future studies on the mechanisms that control retinal growth, we have quantified the proliferation of retinal cells and the length of the cell cycle throughout development. For each day during development, the number of mitotic and postmitotic cells per retina, the proportion of cycling cells, S phase length, and cell cycle length were determined through quantification of cell numbers and 3H-thymidine labeling. As retinal development proceeds, the proportion of cycling cells decreases, and cell cycle length increases, in part due to an increase in S phase length.

[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for John Wiley & Sons, Inc.
    Loading ...
    Write to the Help Desk