Prog Neuropsychopharmacol Biol Psychiatry. 1996 May;20(4):729-35.

Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial.

Barak Y, Levine J, Glasman A, Elizur A, Belmaker RH.

Source

Abarbanel Mental Health Center, Bat Yam, Israel.

Abstract

1. A double-blind controlled crossover trial of 6 gm of inositol daily vs glucose for one month each was carried out in 11 Alzheimer patients. 2. Overall CAMCOG scores showed a trend for greater improvement with inositol that was not significant. 3. Language and orientation improved significantly more on inositol than on placebo. There were no serious side effects. 4. Higher doses of inositol should be studied in Alzheimer's Disease for longer periods.

PMID:: 8843494; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Inositol

LinkOut - more resources

Full Text Sources

Medical

Alzheimer's Disease - MedlinePlus Health Information

Supplemental Content

Related citations

Controlled trials of inositol in psychiatry. [Eur Neuropsychopharmacol. 1997]
Controlled trials of inositol in psychiatry.
Levine J. Eur Neuropsychopharmacol. 1997 May; 7(2):147-55.
A randomized, placebo-controlled dose-comparison trial of haloperidol for psychosis and disruptive behaviors in Alzheimer's disease. [Am J Psychiatry. 1998]
A randomized, placebo-controlled dose-comparison trial of haloperidol for psychosis and disruptive behaviors in Alzheimer's disease.
Devanand DP, Marder K, Michaels KS, Sackeim HA, Bell K, Sullivan MA, Cooper TB, Pelton GH, Mayeux R. Am J Psychiatry. 1998 Nov; 155(11):1512-20.
A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease. [J Neuropsychiatry Clin Neurosci. 1996]
A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease.
Petracca G, Tesón A, Chemerinski E, Leiguarda R, Starkstein SE. J Neuropsychiatry Clin Neurosci. 1996 Summer; 8(3):270-5.
Review Selegiline for Alzheimer's disease. [Cochrane Database Syst Rev. 2003]
Review Selegiline for Alzheimer's disease.
Birks J, Flicker L. Cochrane Database Syst Rev. 2003; (1):CD000442.
Review Galantamine for Alzheimer's disease. [Cochrane Database Syst Rev. 2002]
Review Galantamine for Alzheimer's disease.
Olin J, Schneider L. Cochrane Database Syst Rev. 2002; (3):CD001747.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo co...
Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial.
Prog Neuropsychopharmacol Biol Psychiatry. 1996 May ;20(4):729-35.

PubMed
Microbial degradation of validamycin A by Flavobacterium saccharophilum. Enzymat...
Microbial degradation of validamycin A by Flavobacterium saccharophilum. Enzymatic cleavage of C-N linkage in validoxylamine A.
J Antibiot (Tokyo). 1984 Aug ;37(8):859-67.

PubMed
Reactions involved in bioluminescence systems of limpet (Latia neritoides) and l...
Reactions involved in bioluminescence systems of limpet (Latia neritoides) and luminous bacteria.
Proc Natl Acad Sci U S A. 1972 Aug ;69(8):2086-9.

PubMed
Deafness and peripheral neuropathy following carbon monoxide intoxication--repor...
Deafness and peripheral neuropathy following carbon monoxide intoxication--report of a case.
Folia Psychiatr Neurol Jpn. 1972 Jan ;26(1):35-8.

PubMed
Preliminary pharmacokinetics and pharmacodynamics of an ultra-short-acting opioi...
Preliminary pharmacokinetics and pharmacodynamics of an ultra-short-acting opioid: remifentanil (GI87084B).
Anesth Analg. 1993 Nov ;77(5):1031-40.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: