Am J Kidney Dis. 1996 Oct;28(4):614-7.

Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion.

Lo JC, Chertow GM, Rennke H, Seifter JL.

Source

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Abstract

We report a case of a 44-year-old woman who developed Fanconi's syndrome in association with the oral ingestion of L-lysine. L-lysine is widely available in health food stores and has been recommended in the lay press for the treatment and prevention of recurrent herpes simplex. The development of a severe tubulointerstitial nephritis, and eventual progression to chronic renal failure, underscores the importance of this entity, heretofore unrecognized in humans.

PMID:: 8840955; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

Lysine

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Molecular Biology Databases

L-LYSINE - HSDB

Supplemental Content

Save items

Related citations in PubMed

Tubulointerstitial nephritis and uveitis syndrome (TINU) with Fanconi's syndrome. [Clin Nephrol. 2011]
Tubulointerstitial nephritis and uveitis syndrome (TINU) with Fanconi's syndrome.
Yao YH, Lin CC, Chung YM, Yang AH, Li SY, Lin CC, Lin YP, Yang WC, Yang CY. Clin Nephrol. 2011 Feb; 75 Suppl 1:75-8.
Fanconi's syndrome, interstitial fibrosis and renal failure by aristolochic acid in Chinese herbs. [Pediatr Nephrol. 2006]
Fanconi's syndrome, interstitial fibrosis and renal failure by aristolochic acid in Chinese herbs.
Hong YT, Fu LS, Chung LH, Hung SC, Huang YT, Chi CS. Pediatr Nephrol. 2006 Apr; 21(4):577-9. Epub 2006 Mar 7.
Ranitidine-associated interstitial nephritis and Fanconi syndrome. [Am J Kidney Dis. 1993]
Ranitidine-associated interstitial nephritis and Fanconi syndrome.
Neelakantappa K, Gallo GR, Lowenstein J. Am J Kidney Dis. 1993 Aug; 22(2):333-6.
Review Fanconi's syndrome and distal (type 1) renal tubular acidosis in a patient with primary Sjögren's syndrome with monoclonal gammopathy of undetermined significance. [Clin Nephrol. 2006]
Review Fanconi's syndrome and distal (type 1) renal tubular acidosis in a patient with primary Sjögren's syndrome with monoclonal gammopathy of undetermined significance.
Kobayashi T, Muto S, Nemoto J, Miyata Y, Ishiharajima S, Hironaka M, Asano Y, Kusano E. Clin Nephrol. 2006 Jun; 65(6):427-32.
Review Tubulointerstitial nephritis and Fanconi syndrome in primary biliary cirrhosis. [Am J Kidney Dis. 2005]
Review Tubulointerstitial nephritis and Fanconi syndrome in primary biliary cirrhosis.
Lino M, Binaut R, Noël LH, Patey N, Rustin P, Daniel L, Serpaggi J, Varaut A, Vanhille P, Knebelmann B, et al. Am J Kidney Dis. 2005 Sep; 46(3):e41-6.

See reviews... See all...

Cited by 2 PubMed Central articles

Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report. [Diagn Pathol. 2012]
Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report.
Tanaka M, Setoguchi T, Ishidou Y, Arishima Y, Hirotsu M, Saitoh Y, Nakamura S, Kakoi H, Nagano S, Yokouchi M, et al. Diagn Pathol. 2012 Aug 20; 7:108. Epub 2012 Aug 20.
Fanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient. [Gut Liver. 2010]
Fanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient.
Jung YK, Yeon JE, Choi JH, Kim CH, Jung ES, Kim JH, Park JJ, Kim JS, Bak YT, Byun KS. Gut Liver. 2010 Sep; 4(3):389-93. Epub 2010 Sep 24.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine...
Fanconi's syndrome and tubulointerstitial nephritis in association with L-lysine ingestion.
Am J Kidney Dis. 1996 Oct ;28(4):614-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: