The clinical epidemiology of Alzheimer's disease

Neurol Clin. 1996 May;14(2):337-51. doi: 10.1016/s0733-8619(05)70260-7.

Abstract

Alzheimer's disease is a more common and malignant illness than was appreciated just 2 decades ago. In addition to being a major cause of mortality, it is costly and uniquely distressing for patients and their families. All indications are that the problem will grow as elderly populations expand. Fatalism regarding AD is premature, however. Much has been learned about this disease in only a few years, and it is hoped that this rate of discovery can be maintained or even accelerated in the future.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Age of Onset
  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / epidemiology*
  • Alzheimer Disease / etiology
  • Alzheimer Disease / physiopathology
  • Apolipoprotein E4
  • Apolipoproteins E / adverse effects
  • Apolipoproteins E / genetics
  • Chromosome Aberrations
  • Consanguinity
  • Down Syndrome / complications
  • Estrogens / deficiency
  • Female
  • Global Health
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Risk Factors
  • Sex Distribution

Substances

  • Apolipoprotein E4
  • Apolipoproteins E
  • Estrogens