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1: Acta Odontol Scand. 1996 Jun;54(3):150-3.Links

The effect of two toothpaste detergents on the frequency of recurrent aphthous ulcers.

Herlofson BB, Barkvoll P.

Department of Oral Surgery and Oral Medicine, Dental Faculty, University of Oslo, Norway.

The aim of the present clinical double-blind crossover study was to investigate the effect of two different toothpaste detergents, sodium lauryl sulfate (SLS) and cocoamidopropyl betaine (CAPB), as compared with a detergent-free paste, on 30 patients with frequent occurrences of recurrent aphthous ulcers. The study consisted of three 6-week periods during which the patients brushed twice daily with the different test toothpastes. The localization and number of new ulcers were assessed. A significantly higher frequency of aphthous ulcers was demonstrated when the patients brushed with an SLS- than with a CAPB-containing or a detergent-free placebo paste. An SLS-free toothpaste may thus be recommended for patients with recurrent aphthous ulcers.

PMID: 8811135 [PubMed - indexed for MEDLINE]

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