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Chem Biol. 1996 Aug;3(8):603-9.

Chemokine receptors - the new frontier for AIDS research.

Author information

  • 1Geneva Biomedical Research Institute, Glaxo Wellcome Research and Development, 14 Chemin des Aulx, 1228 Plan les Ouates, Geneva, Switzerland.

Abstract

CD4 is widely known as the HIV receptor, but is insufficient to allow viral infection. Recently, members of the family of chemokine receptors have been identified as the missing co-receptors, which act with CD4 to allow the virus to enter cells. These discoveries open up the possibilities of novel therapeutic strategies to combat HIV infection and AIDS.

PMID:
8807892
[PubMed - indexed for MEDLINE]
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