J Acquir Immune Defic Syndr Hum Retrovirol. 1996;13 Suppl 1:S199-203.

Primary prevention of HTLV-I in Japan.

Hino S, Katamine S, Miyata H, Tsuji Y, Yamabe T, Miyamoto T.

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Department of Virology, Faculty of Medicine, Tottori University, Yonago, Japan.

Abstract

The ATL prevention program (AAP) in the Nagasaki Prefecture since 1987 consists of screening of pregnant women and asking the seropositives to refrain from breast-feeding. We screened approximately 90% of gravidas in the Prefecture and > 90% of the seropositive women agreed not to breast-feed. The maternal transmission rate dropped from approximately 20% to approximately 3%. PCR of cord bloods showed that 2.5% were PCR-positive. However, among formula-fed children, none of the cord-positives seroconverted, and none of the seropositives tested had been cord-positive. Breast-feeding for less than six months decreased the transmission rate significantly, but may have a higher transmission rate than the formula feeding.

PMID:: 8797724; [PubMed - indexed for MEDLINE]

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Cited by 2 PubMed Central articles

Establishment of the milk-borne transmission as a key factor for the peculiar endemicity of human T-lymphotropic virus type 1 (HTLV-1): the ATL Prevention Program Nagasaki. [Proc Jpn Acad Ser B Phys Biol Sci. 2011]
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Primary prevention of HTLV-I in Japan.

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Cited by 2 PubMed Central articles

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