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Ann Rheum Dis. 1996 Jul;55(7):486-8.

Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases.

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  • 1Lupus Pregnancy Clinic, St Thomas' Hospital, London, United Kingdom.

Abstract

OBJECTIVE:

To study maternal and fetal outcome of pregnancy in patients with lupus who were exposed to hydroxychloroquine (HCQ).

METHODS:

The case records of women (n = 33) exposed to HCQ during their pregnancies (n = 36) and of 53 control patients from a single lupus pregnancy centre were reviewed to determine lupus activity, obstetric experience, and infant outcome.

RESULTS:

HCQ was not apparently teratogenic. Lupus activity and obstetric outcome in the two groups were similar.

CONCLUSION:

HCQ continuation is probably safe during pregnancy in patients with lupus, but there is no obvious advantage in commencing treatment.

PMID:
8774170
PMCID:
PMC1010215
[PubMed - indexed for MEDLINE]
Free PMC Article
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