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    Bioorg Khim. 1996 Apr;22(4):256-63.

    [Organization of the gene for the beta-subunit of human photoreceptor cyclic GMP phosphodiesterase].

    [Article in Russian]

    Abstract

    Two recombinant bacteriophage lambda clones encoding a 27.8-kb fragment of the human phosphodiesterase beta-subunit gene were isolated from a human genomic library. The nucleotide sequences of 19 exons (from the 4th to 22nd), 18 introns, and the 3'-flanking region were determined. The analysis of the nucleotide sequence of the phosphodiesterase beta-subunit gene revealed four Alu repeats and four minisatellite regions.

    PMID:
    8768262
    [PubMed - indexed for MEDLINE]

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