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Psychiatr Genet. 1995 Fall;5(3):117-26.

Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32.

Author information

  • 1Department of Neuroscience and Psychological Medicine, Institute of Psychiatry, London, UK.

Erratum in

  • Psychiatr Genet 1996 Spring;6(1):37.

Abstract

Family, twin and adoption studies highlight the influence of genes in the aetiology of schizophrenia, though the mode of inheritance is unclear. We have been conducting a systematic search for major genes in schizophrenia using a series of multiply affected families and report preliminary results of linkage under heterogeneity with markers on chromosome 13. A lod2 score of 1.61 for marker D13S144 was obtained at theta = 0 and alpha of 0.5 and nearby markers also produced positive values.

PMID:
8746410
[PubMed - indexed for MEDLINE]
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