West J Med. 1996 Apr;164(4):321-34.

Cystic fibrosis in adults. From researcher to practitioner.

Source

Dept of Internal Medicine, UC Davis School of Medicine, Sacramento, 95817, USA.

Abstract

The Cystic Fibrosis Foundation currently tracks about 20,000 Americans with cystic fibrosis, an autosomal recessive genetic disease that leads to multisystem complications. With the institution of better therapeutic regimens over the past 2 decades, more patients with this disease are surviving to adulthood. Within the past decade, both clinical and basic science research in the field of cystic fibrosis has progressed at a rapid rate. The intent of this review is to introduce readers to the molecular, cellular, and systemic disorders of this disease. We discuss treatment strategies involving antibiotics, nutrition, immune-response mediators, chest physiotherapy, and sputum-active agents with respect to the airway dysfunction of cystic fibrosis. Other common complications, recent developments, transplantation, and gene therapy are also reviewed.

Comment in

West J Med. 1996 Apr;164(4):361-2.

PMID:: 8732732; [PubMed - indexed for MEDLINE]
PMCID:: PMC1303506

Free PMC Article

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Supplemental Content

Save items

Related citations in PubMed

Review Update on gene therapy for cystic fibrosis. [Curr Opin Mol Ther. 2003]
Review Update on gene therapy for cystic fibrosis.
Griesenbach U, Geddes DM, Alton EW. Curr Opin Mol Ther. 2003 Oct; 5(5):489-94.
Review Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease. [Cochrane Database Syst Rev. 2007]
Review Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease.
Lee T, Southern KW. Cochrane Database Syst Rev. 2007 Apr 18; (2):CD005599. Epub 2007 Apr 18.
Review Toward cystic fibrosis gene therapy. [Annu Rev Med. 1997]
Review Toward cystic fibrosis gene therapy.
Wagner JA, Gardner P. Annu Rev Med. 1997; 48:203-16.
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications. [Hum Gene Ther. 2001]
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications.
Joseph PM, O'Sullivan BP, Lapey A, Dorkin H, Oren J, Balfour R, Perricone MA, Rosenberg M, Wadsworth SC, Smith AE, et al. Hum Gene Ther. 2001 Jul 20; 12(11):1369-82.
Review Cystic fibrosis. [Lancet. 2003]
Review Cystic fibrosis.
Ratjen F, Döring G. Lancet. 2003 Feb 22; 361(9358):681-9.

See reviews... See all...

Cited by 2 PubMed Central articles

Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. [Antimicrob Agents Chemother. 2...]
Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa.
Khalil H, Chen T, Riffon R, Wang R, Wang Z. Antimicrob Agents Chemother. 2008 May; 52(5):1635-41. Epub 2008 Feb 19.
Review Cystic fibrosis therapy--where we are and how we got there. [West J Med. 1996]
Review Cystic fibrosis therapy--where we are and how we got there.
Gruenert DC. West J Med. 1996 Apr; 164(4):361-2.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Cystic fibrosis in adults. From researcher to practitioner.
Cystic fibrosis in adults. From researcher to practitioner.
West J Med. 1996 Apr ;164(4):321-34.

PubMed
Obstetrical brachial plexus injury in newborn babies delivered by caesarean sect...
Obstetrical brachial plexus injury in newborn babies delivered by caesarean section.
J Hand Surg Br. 1996 Apr ;21(2):263-5.

PubMed
Analysis of hepatitis B virus precore variants in hepatitis B e antibody-positiv...
Analysis of hepatitis B virus precore variants in hepatitis B e antibody-positive patients treated with prednisone plus interferon.
J Viral Hepat. 1995 ;2(6):279-84.

PubMed
[An approach to the diagnosis of recurrent attack of rheumatic fever in patients...
[An approach to the diagnosis of recurrent attack of rheumatic fever in patients with rheumatic heart disease].
Zhonghua Nei Ke Za Zhi. 1995 Oct ;34(10):687-9.

PubMed
A basis for differentiating among the multiple human Mu-glutathione S-transferas...
A basis for differentiating among the multiple human Mu-glutathione S-transferases and molecular cloning of brain GSTM5.
J Biol Chem. 1993 Apr 25 ;268(12):8893-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Cystic fibrosis in adults. From researcher to practitioner.

Source

Abstract

Comment in

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 2 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information