Send to:

Choose Destination
See comment in PubMed Commons below
Baillieres Clin Neurol. 1996 Mar;5(1):65-75.

Wallerian degeneration in peripheral nerve disease.

Author information

  • 1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.


Wallerian-like degeneration can be regarded as the final shared pathway of the most prevalent diseases of the peripheral nervous system, including many degenerative, metabolic, heritable, toxic, inflammatory and ischaemic disorders. The cellular responses that take place during Wallerian degeneration, including the elaboration of neurotrophins, are increasingly recognized to set the stage for the success or failure of subsequent regeneration, and manipulations of Wallerian degeneration are being investigated as a potential means of altering the outcome of nerve regeneration.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk