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Scand J Gastroenterol. 1996 Apr;31(4):355-61.

Incidence of Crohn's disease in four counties in southeastern Norway, 1990-93. A prospective population-based study. The Inflammatory Bowel South-Eastern Norway (IBSEN) Study Group of Gastroenterologists.

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  • 1Dept. of Internal Medicine, Ostfold Central Hospital, Fredrikstad, Sweden.

Abstract

BACKGROUND:

Standardized criteria for Crohn's disease (CD) have only recently been developed, and prospective community-based incidence studies have been performed only during the past 3 decades. Geographic variations in incidence may therefore be due to differences in study design.

METHODS:

From 1 January 1990 to 31 December 1993 all new cases of CD in four counties in southeastern Norway were prospectively registered.

RESULTS:

A total of 225 new cases yielded an annual incidence of 5.8/10(5), with the highest incidence in mixed rural-urban areas. A peak of 11.2/10(5) in the annual incidence was found for the age group 15 to 24 years, with no significant differences in the overall annual incidence by gender. An average duration of 6 months of disease before diagnosis was unchanged during the 4 years. About half of the patients had isolated colonic disease, and one-quarter had isolated small-bowel disease.

CONCLUSIONS:

This study confirms the high incidence figures for Scandinavia, with a particularly high incidence in mixed rural-urban areas. Ileocolonoscopy improves the accuracy of the diagnosis and of the determination of disease extent, which may have therapeutic implications for the treatment and follow-up of patients.

PMID:
8726303
[PubMed - indexed for MEDLINE]
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