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1: Immunol Cell Biol. 1995 Dec;73(6):489-504.Links

The ecology and pathology of Epstein-Barr virus.

Schmidt CW, Misko IS.

Queensland Institute of Medical Research, The Bancroft Centre, Brisbane, Australia.

Epstein-Barr virus achieves its ubiquitous and uniform epidemiological distribution by a dual strategy of latency to guarantee lifelong persistence and intermittent replication to guarantee transmission. These two functions appear to dictate residence in different cell types: latency in B lymphocytes and replication in epithelial cells. Both of these cell compartments are potential sites for EBV-associated malignancies.

PMID: 8713470 [PubMed - indexed for MEDLINE]