Time to peak serum antibody response to influenza vaccine in the elderly

Clin Diagn Lab Immunol. 1996 May;3(3):361-2. doi: 10.1128/cdli.3.3.361-362.1996.

Abstract

The earliest time at which serum antibody peaks following administration of influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 2 and 4 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91(H1N1), A/Shangdong/9/93(H3N2), and B/Panama/45/90 was used. The hemagglutination inhibition antibody titers at 2 weeks after vaccination were identical to the hemagglutination inhibition antibody titers at 4 weeks for all three vaccine components.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged*
  • Aged, 80 and over
  • Antibody Formation / immunology
  • Female
  • Hemagglutination Inhibition Tests
  • Humans
  • Influenza Vaccines / immunology*
  • Male
  • Time Factors

Substances

  • Influenza Vaccines