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Eur J Gastroenterol Hepatol. 1995 Nov;7(11):1093-7.

Cholescintigraphy in patients with acute cholecystitis before and after percutaneous gallbladder drainage.

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  • 1Department of Medical Gastroenterology, Hvidovre Hospital, University of Copenhagen, Denmark.

Abstract

OBJECTIVE:

To investigate gallbladder function by use of cholescintigraphy in patients with acute cholecystitis before and after percutaneous gallbladder drainage.

DESIGN:

A cholescintigraphy was performed in 40 patients with acute cholecystitis before and after the performance of percutaneous gallbladder drainage. During the post-drainage cholescintigraphies, a cholecystokinin stimulation was performed to investigate gallbladder emptying in 12 selected patients. Gallbladder pressure and volume were measured before drainage in another group of 12 patients with acute cholecystitis.

RESULTS:

As expected, no gallbladder activity was observed in the cholescintigraphies before drainage, except in a patient with an occluding stone in the common bile duct. Cystic duct patency and gallbladder activity were seen in 80% of patients in cholescintigraphies performed after drainage but before any other treatment. Post-drainage cholescintigraphy revealed a mean gallbladder ejection fraction of 24%, which is significantly lower than the corresponding value in normal individuals and gallstone patients without cholecystitis (n = 12). Gallbladder pressure and volume were markedly increased compared with normal values.

CONCLUSION:

The relief of increased gallbladder pressure and volume appears to be important for the re-establishment of gallbladder function.

PMID:
8680910
[PubMed - indexed for MEDLINE]
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