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Gene. 1996 Jun 1;171(2):291-4.

Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit.

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  • 1Center For Blood Research, Harvard Medical School, Boston, MA 02115, USA.


We isolated a partial genomic clone encoding ITGAD, a novel beta 2-integrin alpha subunit. The ITGAD gene is highly homologous to the three previously known alpha subunit-encoding genes, that compose the beta 2 integrin family, in deduced amino acid sequence, intron/exon structure and mapping location (chromosome 16p11).

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