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Curr Opin Genet Dev. 1995 Oct;5(5):552-8.

Molecular mechanisms of cell-type determination in budding yeast.

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  • Department of Microbiology and Immunology, University of California, San Francisco 94143, USA.


Studies of cell-type determination in the yeast Saccharomyces cerevisiae have revealed a regulatory network of proteins that are highly conserved in evolutionary terms. In the past few years, genetic, biochemical, and structural approaches have shown what many of these components do, how they fit together, and how they cooperate to regulate the expression of many different target genes.

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