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Gene. 1996 Mar 9;169(2):247-9.

Olfactory receptor-encoding genes and pseudogenes are expressed in humans.

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  • 1Protein Engineering Department, Institute of Food Research, Reading, UK.


A putative olfactory receptor-encoding gene was cloned from human genomic DNA and shown to be expressed by isolation of a full-length cDNA from olfactory tissue. A second cDNA clone was found to encode an olfactory receptor pseudogene. The expression of a pseudogene from the olfactory gene repertoire, in neurons which express only a single receptor type, implies that many neurons will be non-functional.

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