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    J Pediatr Gastroenterol Nutr. 1996 Feb;22(2):153-6.

    Colonic strictures in patients with cystic fibrosis: results of a survey of 114 cystic fibrosis care centers in the United States.

    Source

    Epidemiology Branch, Food and Drug Administration, Rockville, Maryland, USA.

    Abstract

    We describe 15 cases of stricture of the colon requiring surgery in cystic fibrosis patients identified from a survey of 114 cystic fibrosis care centers in the United States. Patient ages ranged from 2 to 8 years, seven of the 15 patients were female. A history of meconium ileus was reported in nine of the 15 cases. Fibrosis of the submucosa was described in 14 surgical pathology reports. Pancreatic enzyme use history was available from 14 reports. All had taken delayed-release products for 6-96 months at average doses ranging from 6,700 to 29,100 units lipase/kg/meal, but only eight of them used products containing >20,000 units lipase per capsule prior to surgery.

    PMID:
    8642487
    [PubMed - indexed for MEDLINE]

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