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Infect Immun. 1996 Mar;64(3):1039-42.

Alteration of gonococcal protein expression in acidic culture.

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  • 1Department of Biology, Western Oregon State College, Monmouth, 97361, USA.

Abstract

We grew Neisseria gonorrhoeae under acidic, neutral, and alkaline conditions and noted altered expression of at least 12 outer membrane proteins between 31 and 100 kDa in size. One protein whose expression was upregulated under acidic conditions was gonococcal heat shock protein 63. These proteins may contribute to the pathogenesis of gonorrhea in the urogenital tract.

PMID:
8641756
[PubMed - indexed for MEDLINE]
PMCID:
PMC173877
Free PMC Article
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