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Int Arch Allergy Immunol. 1996 Apr;109(4):352-5.

Group 5 allergens of timothy grass (Phl p 5) bear cross-reacting T cell epitopes with group 1 allergens of rye grass (Lol p 1).

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  • 1Institut für Klinische Immunologie, Friedrich-Schiller-Universität, Jena, Germany.

Abstract

Selected human T cell clones reactive with group 5 allergens of timothy grass (Phl p 5) were cross-stimulated in specific proliferation assays with group 1 allergens of rye grass (Lol p 1). Such interspecies cross-reactivities result obviously from structural motifs presented on defined Phl p 5 fragments as shown with recombinant Phl p 5 products.

PMID:
8634519
[PubMed - indexed for MEDLINE]
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