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    FEBS Lett. 1996 Mar 18;382(3):276-80.

    Human testis specifically expresses a homologue of the rodent T lymphocytes RT6 mRNA.

    Lévy I, Wu YQ, Roeckel N, Bulle F, Pawlak A, Siegrist S, Mattéi MG, Guellaën G.

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    Unite INSERM 99, Hopital Henri Mondor, Creteil, France.

    Abstract

    A human homologue of the rodent T cell mono ADP-ribosyl transferase RT6 mRNA was identified by a systematic analysis of human testis transcripts. This messenger encodes for a precursor protein of 367 aa (MW: 41.5 kDa) which exhibits a peptide signal, consensus domains for mono ADP-ribosyl transferase and a C-terminal part characteristic of glycophosphatidyl inositol anchored protein. This mRNA, transcribed from a gene localized in 4q13-q21, is not expressed in white blood cells but is specific for human testis in which it is likely to correspond to a new ADP-ribosyl transferase.

    PMID:
    8605984
    [PubMed - indexed for MEDLINE]

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