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Arch Neurol. 1996 Jan;53(1):101-3.

BK virus encephalitis in an immunocompetent patient.

Author information

  • 1Department of Neurology, Klinikum Grosshadern, Munich, Germany.

Abstract

OBJECTIVES:

To describe a previously healthy patient now suffering from monophasic encephalitis caused by a primary infection with BK virus and to discuss possible risk factors for developing BK virus encephalitis.

DESIGN:

Case report.

SETTING:

Referral hospital.

PATIENT:

The patient was examined on referral.

MAIN OUTCOME MEASURES:

The main diagnostic tests performed were serology, polymerase chain reaction on cerebrospinal fluid samples, and cranial magnetic resonance imaging.

RESULTS:

During the course of the patient's encephalitis, an IgM titer developed against polyomavirus, followed by anti-polyomavirus IgG. Wild-type BK virus was demonstrated in cerebrospinal fluid samples. Cranial magnetic resonance imaging showed diffuse reversible white matter changes most prominent on T2-weighted images.

CONCLUSION:

We conclude that diagnostic tests for BK, a human polyomavirus, should be included in the screening program for encephalitogenic pathogens.

PMID:
8599551
[PubMed - indexed for MEDLINE]
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