Ann N Y Acad Sci. 1995 Dec 29;774:128-42.

Replacement of DHEA in aging men and women. Potential remedial effects.

Source

Department of Reproductive Medicine, University of California, San Diego, La Jolla 92093, USA.

Abstract

DHEA in appropriate replacement doses appears to have remedial effects with respect to its ability to induce an anabolic growth factor, increase muscle strength and lean body mass, activate immune function, and enhance quality of life in aging men and women, with no significant adverse effects. Further studies are needed to confirm and extend our current results, particularly the gender differences.

PMID:: 8597453; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Supplemental Content

Save items

Related citations in PubMed

The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. [Clin Endocrinol (Oxf). 1998]
The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women.
Morales AJ, Haubrich RH, Hwang JY, Asakura H, Yen SS. Clin Endocrinol (Oxf). 1998 Oct; 49(4):421-32.
Endocrine and metabolic effects of long-term administration of [Nle27]growth hormone-releasing hormone-(1-29)-NH2 in age-advanced men and women. [J Clin Endocrinol Metab. 1997]
Endocrine and metabolic effects of long-term administration of [Nle27]growth hormone-releasing hormone-(1-29)-NH2 in age-advanced men and women.
Khorram O, Laughlin GA, Yen SS. J Clin Endocrinol Metab. 1997 May; 82(5):1472-9.
The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods. [Contemp Clin Trials. 2007]
The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods.
von Mühlen D, Laughlin GA, Kritz-Silverstein D, Barrett-Connor E. Contemp Clin Trials. 2007 Feb; 28(2):153-68. Epub 2006 May 6.
Review Effects of dehydroepiandrosterone on bone mineral density: what implications for therapy? [Treat Endocrinol. 2002]
Review Effects of dehydroepiandrosterone on bone mineral density: what implications for therapy?
Villareal DT. Treat Endocrinol. 2002; 1(6):349-57.
Review Androgen therapy with dehydroepiandrosterone. [World J Urol. 2003]
Review Androgen therapy with dehydroepiandrosterone.
Buvat J. World J Urol. 2003 Nov; 21(5):346-55. Epub 2003 Oct 10.

See reviews... See all...

Cited by 8 PubMed Central articles

Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women. [Arch Womens Ment Health. 2010]
Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women.
Morgan ML, Rapkin AJ, Biggio G, Serra M, Pisu MG, Rasgon N. Arch Womens Ment Health. 2010 Feb; 13(1):91-8. Epub 2009 Sep 3.
Circulating dehydroepiandrosterone sulfate concentrations during the menopausal transition. [J Clin Endocrinol Metab. 2009]
Circulating dehydroepiandrosterone sulfate concentrations during the menopausal transition.
Crawford S, Santoro N, Laughlin GA, Sowers MF, McConnell D, Sutton-Tyrrell K, Weiss G, Vuga M, Randolph J, Lasley B. J Clin Endocrinol Metab. 2009 Aug; 94(8):2945-51. Epub 2009 May 26.
Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements. [FASEB J. 2009]
Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements.
Henderson GC, Dhatariya K, Ford GC, Klaus KA, Basu R, Rizza RA, Jensen MD, Khosla S, O'Brien P, Nair KS. FASEB J. 2009 Feb; 23(2):631-41. Epub 2008 Sep 30.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Replacement of DHEA in aging men and women. Potential remedial effects.
Replacement of DHEA in aging men and women. Potential remedial effects.
Ann N Y Acad Sci. 1995 Dec 29 ;774:128-42.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Replacement of DHEA in aging men and women. Potential remedial effects.

Source

Abstract

Publication Types, MeSH Terms, Substances, Grant Support

Publication Types

MeSH Terms

Substances

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 8 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information