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Br J Cancer. 1996 Feb;73(4):553-6.

Human papillomavirus infection and risk of progression of epithelial abnormalities of the cervix.

Author information

  • 1Centre for Cancer Epidemiology, Christie Hospital NHS Trust, Manchester, UK.

Abstract

The polymerase chain reaction has been used to determine the presence of human papillomavirus (HPV) 16 and HPV 18 DNA sequences in archival histological material removed from a cohort of untreated women with cervical epithelial abnormalities. The detection of HPV 16 or HPV 18 DNA sequences in the initial biopsy specimen was associated with a significantly increased risk of subsequent disease progression.

PMID:
8595174
[PubMed - indexed for MEDLINE]
PMCID:
PMC2074466
Free PMC Article
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