Klin Wochenschr. 1977 Apr 15;55(8):379-84.

[Biochemical characterization of a new variant of glucose-6-phosphate dehydrogenase (G-6-PD) deficiency with favism: G-6-PD Bielefeld (author's transl)].

[Article in German]

Abstract

A new variant of G-6-PD with favism has been detected in a German family. After partial purification the enzyme was biochemically characterized. It revealed normal electrophoretic mobility, normal thermostability and a flat pH-activity curve. The Km-value for G-6-P was reduced, whereas this value was normal for NADP. The substrate analogues 2-desoxy G-6-P, Gal-6-p and deamino-NADP were utilized to increased rates. The biochemical data were compatible with the benign clinical course.

PMID:: 859288; [PubMed - indexed for MEDLINE]

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Glucosephosphate Dehydrogenase

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Characteristics of a new abnormal variant of G-6-PD in human red cells. [Acta Biol Med Ger. 1977]
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Cited by 1 PubMed Central article

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