Hum Mol Genet. 1995 Nov;4(11):2159-63.

Localization of a gene for non-syndromic hearing loss (DFNA5) to chromosome 7p15.

van Camp G, Coucke P, Balemans W, van Velzen D, van de Bilt C, van Laer L, Smith RJ, Fukushima K, Padberg GW, Frants RR, et al.

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Department of Medical Genetics, University of Antwerp (UIA), Belgium.

Abstract

Progressive hearing loss affects approximately 50% of the elderly by the age of 80, and is most likely caused by an interaction of genetic and environmental factors. Identification of the genes responsible for hereditary hearing loss is therefore important. Families with pure genetic degenerative hearing disorders may be helpful as the same genes may be also involved in age-related hearing loss in general. In this study we have performed a genome search in an extended Dutch family with autosomal dominant progressive hearing loss starting in the high frequencies. The gene causing hearing loss in this family was localized to the short arm of chromosome 7, in a 15 cM interval between markers D7S493 and D7S632.

PMID:: 8589696; [PubMed - indexed for MEDLINE]

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[Mapping of gene underlying autosomal dominant non-syndromic hearing loss(DFNA)]. [Yi Chuan. 2006]
[Mapping of gene underlying autosomal dominant non-syndromic hearing loss(DFNA)].
Sun HJ, Tao R, Cheng J, Yang SZ, Cao JY, Yu LM, Hong MD, Feng GY, Dai P, Yuan HJ, et al. Yi Chuan. 2006 Dec; 28(12):1489-94.
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Review Non-syndromic dominant sensorineural hearing loss: from a few phenotypes to many genotypes.
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Localization of a gene for non-syndromic hearing loss (DFNA5) to chromosome 7p15...
Localization of a gene for non-syndromic hearing loss (DFNA5) to chromosome 7p15.
Hum Mol Genet. 1995 Nov ;4(11):2159-63.

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Localization of a gene for non-syndromic hearing loss (DFNA5) to chromosome 7p15.

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