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Biochem Biophys Res Commun. 1996 Jan 5;218(1):210-6.

Identification of the S-Endo 1 endothelial-associated antigen.

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  • 1Laboratoire d'Hématologie, Faculté de pharmacie, Marseille, France.


We have recently described a monoclonal antibody, S-Endo 1, recognizing a molecule constitutively expressed in all types of human endothelial cells. We showed that this protein around 118 kDa and located at the endothelial cell-cell junction presented sequence identity with MUC18 described as a tumor marker in human melanoma. The difference in antibodies immunoreactivity and antigen molecular weight heterogeneity observed between various cell types strongly suggested S-Endo 1 antigen isoforms expression.

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