Send to:

Choose Destination
See comment in PubMed Commons below
Cancer Lett. 1996 Jan 19;99(1):115-9.

trans,trans-2,4-decadienal: cytotoxicity and effect on glutathione level in human erythroleukemia (HEL) cells.

Author information

  • 1URA CNRS 1485, Facult├ęs de M├ędecine et de Pharmacie, Limoges, France.


The effects of trans,trans-2,4-decadienal (DDE), an isomer of a lipid peroxidation product were investigated on the human erythroleukemia cell line (HEL TIB 180). DDE strongly inhibits cell growth and affects cell viability without any differentiating effects. DDE treatment of HEL cells leads to a marked variation of the cellular glutathione level (GSH) and is involved in the beginning of DNA fragmentation.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk