Format

Send to:

Choose Destination
See comment in PubMed Commons below
Support Care Cancer. 1995 Nov;3(6):414-7.

Nature and outcome of febrile episodes in patients with pancreatic and hepatobiliary cancer.

Author information

  • 1Department of Medical Specialities, University of Texas, M.D. Anderson Cancer Center, Houston 77030, USA.

Abstract

Fifty febrile episodes in patients with hepatobiliary and pancreatic cancer were reviewed. Biliary obstruction often resulting in cholangitis was an important predisposing factor, whereas neutropenia (< 500 PMN/mm3) was uncommon (10%). Microbiologically documented infections originating from the gastrointestinal tract were predominant, with Enterococcus faecalis and Escherichia coli being isolated most often. Non-infectious causes of fever occurred in 16% of patients. Only one patient developed a fungal infection. The overall response rate to therapy was 94%, with 32% being eligible for outpatient management. These data are quite different from those generated from patients with hematologic malignancies and indicate that disease-site specific management guidelines need to be developed for febrile episodes in patients with various underlying neoplasms.

Comment in

PMID:
8564346
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk