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J Urol. 1996 Feb;155(2):607-9.

Transrectal ultrasound guided prostatic nerve blockade eases systematic needle biopsy of the prostate.

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  • 1Department of Urology, University of California School of Medicine, San Francisco, USA.

Abstract

PURPOSE:

We assessed the effect of transrectal ultrasound guided prostatic nerve blockade on the discomfort associated with systematic needle biopsy of the prostate.

MATERIALS AND METHODS:

A prospective randomized double-blind study was performed of 64 patients requiring systematic biopsy of the prostate. Patients were randomly assigned to receive an injection of 5 ml. 1% lidocaine or 5 ml. saline (0.9% sodium chloride) at the vascular pedicle on 1 side of the prostate only. They were then asked to score the severity of discomfort of the injection and subsequent biopsies on each side.

RESULTS:

Mean pain scores were significantly lower on the side with than the side without lidocaine injection (1.6 +/- 0.9 versus 2.4 +/- 1.2, p < 0.0001) and not significantly different when saline was injected (2.9 +/- 1.2 versus 3.0 +/- 1.1, p = 0.52). Pain scores were significantly different when the lidocaine injected side was compared to the saline solution injected side (p < 0.0001) but the difference was not significant between the noninjected sides of the 2 groups (p = 0.076). Of the patients in the lidocaine group 68% reported that they would prefer to undergo biopsy with the injection compared to only 41% in the placebo group (p = 0.037). During the study no patient in either group had any adverse effect from the injection.

CONCLUSIONS:

Transrectal ultrasound guided nerve blockade before prostatic biopsy results in a more comfortable procedure for the patient.

PMID:
8558671
[PubMed - indexed for MEDLINE]
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