J Dev Behav Pediatr. 1995 Oct;16(5):327-32.

School-age follow-up of a single-dose prophylactic surfactant cohort.

Wagner CL, Kramer BM, Kendig JW, Brooks JG, Cox C, Wagner MT, Phelps DL.

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Department of Pediatrics, University of Rochester Medical Center, New York, USA.

Abstract

This study reports the school-age developmental and health status of a preventilatory surfactant cohort. The sample consisted of 39 surviving subjects (21 experimental and 18 controls) born at 25 to 29 weeks gestation who were studied at 6 and 12 months and 5 to 7 years of age. At 6- and 12-month follow-ups, the cohort was functioning close to the population normative mean. Although cognitive and motor assessments at school age also showed no group differences, 8 of 19 (42%) in the surfactant group and 9 of 17 (53%) in the normal saline group attained a McCarthy General Cognitive Index score of < or = 84 (abnormal range). On the Connors' Parental Questionnaire, both groups scored high on the Learning Disability Subscale. The surviving cohort at 5 to 7 years had no identified long-term sequelae due to surfactant therapy, yet both groups were at risk for neurodevelopmental and educational morbidity.

PMID:: 8557832; [PubMed - indexed for MEDLINE]

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School-age follow-up of a single-dose prophylactic surfactant cohort.
School-age follow-up of a single-dose prophylactic surfactant cohort.
J Dev Behav Pediatr. 1995 Oct ;16(5):327-32.

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School-age follow-up of a single-dose prophylactic surfactant cohort.

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