Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Epidemiol Infect. 1995 Dec;115(3):591-601.

Analysis of influenza A virus reinfection in children in Japan during 1983-91.

Author information

  • 1Department of Microbiology, Institute of Public Health, Tokyo, Japan.

Abstract

The epidemiology of influenza A in Japan was studied during 1979-91 and viruses isolated from reinfections during 1983-91 were analysed. Of 2963 influenza viruses isolated from reinfections during 1983-91 were analysed. Of 2963 influenza viruses isolated during this period, 922 and 1006 were influenza A(H1N1) and A(H3N2) viruses respectively; the others were influenza B viruses. Influenza A(H1N1) and A(H3N2) caused 5 and 6 epidemics respectively, most accompanied by antigenic drift. Seventeen reinfections with H1N1 and 17 with H3N2 were detected during our study. The primary and reinfection strains isolated from 7 H1N1 and 10 H3N2 cases were studied by haemagglutination-inhibition, and amino acid and nucleotide sequences of the HA1 region of the haemagglutinin. Most of the primary and reinfection strains were antigenically and genetically similar to the epidemic viruses circulating at that time. However, in 4 out of 10 cases of reinfection with influenza H3N2 virus, reinfection strains were genetically different from the epidemic viruses.

PMID:
8557091
[PubMed - indexed for MEDLINE]
PMCID:
PMC2271582
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Write to the Help Desk