Wien Klin Wochenschr. 1977 Apr 15;89(8):265-9.

[Acute poisoning with tricylic antidepressants and treatment with physostigmine salicylate (author's transl)].

[Article in German]

Czech K, Francesconi M, Haimböck E, Hruby K.

Abstract

Three cases of self poisoning with tricyclic antidepressants (TAD) are reported, one of them with a potentially lethal dose. All three cases were treated with physostigmine salicylate (PS) and in two cases there was complete reversal of coma within a few minutes. In striking contrast to the reported high incidence of cardiac arrhythmias no cardiac complications were observed in any of the cases. Therefore we think that the use of PS should be considered when treating cases of TAD poisoning.

PMID:: 855346; [PubMed - indexed for MEDLINE]

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The use of physostigmine as an antidote in tricyclic anti-depressant intoxication. [Acta Anaesthesiol Scand. 1978]
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