Natural history of untreated cytomegalovirus retinitis

E F Bowen; P Wilson; M Atkins; S Madge; P D Griffiths; M A Johnson; V C Emery

doi:10.1016/s0140-6736(95)92842-1

Natural history of untreated cytomegalovirus retinitis

Lancet. 1995 Dec;346(8991-8992):1671-3. doi: 10.1016/s0140-6736(95)92842-1.

Authors

E F Bowen¹, P Wilson, M Atkins, S Madge, P D Griffiths, M A Johnson, V C Emery

Affiliation

¹ Department of Virology, Royal Free Hospital School of Medicine, Hampstead, London, UK.

PMID: 8551826
DOI: 10.1016/s0140-6736(95)92842-1

Abstract

Cytomegalovirus infection is common in patients with AIDS, and often causes retinitis. Treatment is rarely curative, but the progression of retinitis is delayed. The untreated course of cytomegalovirus retinitis in AIDS is unknown. We report a 35-year-old man with retinitis who refused treatment. Retinitis resulted in blindness within 6 months. Measurement of cytomegalovirus genomes showed an increasing viral load in blood and urine.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Acquired Immunodeficiency Syndrome / complications
Adult
Blindness / etiology
Blood / virology
Cytomegalovirus / genetics
Cytomegalovirus Retinitis / complications*
Cytomegalovirus Retinitis / virology
Genome, Viral
Humans
Male
Urine / virology