Immunoglobulin allotypes and RFLPs in disease asso...[Exp Clin Immunogenet. 1995]

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1: Exp Clin Immunogenet. 1995;12(3):198-205.Links

Immunoglobulin allotypes and RFLPs in disease association.

Propert D.

Department of Applied Biology and Biotechnology, Royal Melbourne Institute of Technology, Vic., Australia.

Immunoglobulin heavy chain (Gm) and light chain (Km) allotypes have been extensively studied as possible markers of susceptibility to a range of immune-related diseases including malignancies, infectious diseases and autoimmune disorders. This review is concentrated on susceptibility to multiple sclerosis, systemic lupus erythematosus and insulin-dependent diabetes mellitus.

PMID: 8534506 [PubMed - indexed for MEDLINE]

ReviewGm and Km allotypes in autoimmune diseases. [G Ital Cardiol. 1992]
Susceptibility to multiple sclerosis associated with an immunoglobulin gamma 3 restriction fragment length polymorphism. [J Clin Invest. 1987]
Immunoglobulin allotypes in systemic lupus erythematosus--results of a central European multicenter study. SLE Study Group. [Exp Clin Immunogenet. 1991]
Gm allogenotype distribution and lack of HLA-DR, Gm interaction in SLE and CREST/PSS. [Immunol Cell Biol. 1989]
ReviewAdvances in human immunoglobulin allotypes. [Exp Clin Immunogenet. 1995]

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Immunoglobulin allotypes and RFLPs in disease association.

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