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Division of Neurological Surgery, University of Alabama, Birmingham, USA.
This article offers a broad review of cerebral autoregulation to help understand the principles of cerebral perfusion pressure (CPP) management. Discussed are cerebral autoregulation, Poiseuille's law, mannitol-induced hypertension and CPP, prognosis by CPP, management of CPP, and a summary of physiologic basis for CPP management.
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