Cytogenet Cell Genet. 1995;71(4):374-6.

Regional assignment of the human 4-hydroxyphenylpyruvate dioxygenase gene (HPD) to 12q24-->qter by fluorescence in situ hybridization.

Stenman G, Röijer E, Rüetschi U, Dellsén A, Rymo L, Lindstedt S.

Source

Laboratory of Cancer Genetics, Department of Pathology, Göteborg University, Sweden.

Abstract

Using a panel of human-rodent somatic cell hybrids, we have previously mapped the gene (HPD, previously called PPD) encoding 4-hydroxyphenylpyruvate dioxygenase to the distal half of the long arm of human chromosome 12, region q14-->qter. To obtain a genomic probe useful for fluorescence in situ hybridization (FISH) analysis we screened a human leukocyte genomic library and isolated a 13.4-kb phage clone, which by restriction fragment and sequence analyses was shown to contain exons 1-10 of HPD and approximately 2-kb upstream sequences. We now report the subregional localization of HPD to 12q24-->qter based on two color FISH analysis employing this clone.

PMID:: 8521727; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances, Secondary Source ID

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

Secondary Source ID

GENBANK/U29895

LinkOut - more resources

Medical

HPD Gene - Genetics Home Reference

Supplemental Content

Save items

Related citations in PubMed

Genomic organization and chromosomal localization of the gene encoding human P-selectin glycoprotein ligand. [J Biol Chem. 1995]
Genomic organization and chromosomal localization of the gene encoding human P-selectin glycoprotein ligand.
Veldman GM, Bean KM, Cumming DA, Eddy RL, Sait SN, Shows TB. J Biol Chem. 1995 Jul 7; 270(27):16470-5.
Expression and post-translational modification of human 4-hydroxy-phenylpyruvate dioxygenase. [Cell Biol Int. 2002]
Expression and post-translational modification of human 4-hydroxy-phenylpyruvate dioxygenase.
Aarenstrup L, Falch AM, Jakobsen KK, Neve S, Henriksen L LØ, Tommerup N, Leffers H, Kristiansen K. Cell Biol Int. 2002; 26(7):615-25.
Cloning, structural analysis, and chromosomal localization of the human CSRP2 gene encoding the LIM domain protein CRP2. [Genomics. 1997]
Cloning, structural analysis, and chromosomal localization of the human CSRP2 gene encoding the LIM domain protein CRP2.
Weiskirchen R, Erdel M, Utermann G, Bister K. Genomics. 1997 Aug 15; 44(1):83-93.
Human 4-hydroxyphenylpyruvate dioxygenase gene (HPD). [Genomics. 1997]
Human 4-hydroxyphenylpyruvate dioxygenase gene (HPD).
Rüetschi U, Rymo L, Lindstedt S. Genomics. 1997 Sep 15; 44(3):292-9.
Assignment of the human folate transporter gene to chromosome 21q22.3 by somatic cell hybrid analysis and in situ hybridization. [Biochem Biophys Res Commun. 1995]
Assignment of the human folate transporter gene to chromosome 21q22.3 by somatic cell hybrid analysis and in situ hybridization.
Yang-Feng TL, Ma YY, Liang R, Prasad PD, Leibach FH, Ganapathy V. Biochem Biophys Res Commun. 1995 May 25; 210(3):874-9.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Gene
Gene records that cite the current articles. Citations in Gene are added manually by NCBI or imported from outside public resources.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
HomoloGene
HomoloGene clusters of homologous genes and sequences that cite the current articles. These are references on the Gene and sequence records in the HomoloGene entry.
Nucleotide
Primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
Nucleotide (RefSeq)
NCBI nucleotide Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (RefSeq)
NCBI protein Reference Sequences (RefSeqs) that are cited in the current articles, included in the corresponding Gene Reference into Function, or that include the PubMed articles as references.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
Taxonomy via GenBank
Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
UniGene
UniGene clusters of expressed sequences that are associated with the current articles through references on the clustered sequence records and related Gene records.
Protein
Protein translation features of primary database (GenBank) nucleotide records reported in the current articles as well as Reference Sequences (RefSeqs) that include the articles as references.
GEO Profiles
Gene Expression Omnibus (GEO) Profiles of molecular abundance data. The current articles are references on the Gene record associated with the GEO profile.

Recent activity

Clear Turn Off Turn On

Regional assignment of the human 4-hydroxyphenylpyruvate dioxygenase gene (HPD) ...
Regional assignment of the human 4-hydroxyphenylpyruvate dioxygenase gene (HPD) to 12q24-->qter by fluorescence in situ hybridization.
Cytogenet Cell Genet. 1995 ;71(4):374-6.

PubMed
Clinical relevance of drug interactions with lithium.
Clinical relevance of drug interactions with lithium.
Clin Pharmacokinet. 1995 Sep ;29(3):172-91.

PubMed
Assembly of phage Mu transpososomes: cooperative transitions assisted by protein...
Assembly of phage Mu transpososomes: cooperative transitions assisted by protein and DNA scaffolds.
Cell. 1995 Nov 3 ;83(3):375-85.

PubMed
Self-esteem and obesity in children and adolescents: a literature review.
Self-esteem and obesity in children and adolescents: a literature review.
Obes Res. 1995 Sep ;3(5):479-90.

PubMed
Crystallization of the chaperone protein SecB.
Crystallization of the chaperone protein SecB.
Protein Sci. 1995 Aug ;4(8):1651-3.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: