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J Assist Reprod Genet. 1995 Mar;12(3):187-90.

Epidural anesthesia in an in vitro fertilization and embryo transfer program.

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  • 1Ecocenter and Fertility Center, Clinica C. G. Ruesch, Napoli, Italy.

Abstract

OBJECTIVES:

To investigate the potential advantages of epidural anesthesia in an in vitro fertilization and embryo transfer program.

STUDY DESIGN:

Between January 1991 and December 1992, 148 infertile patients underwent transvaginal ultrasound guided oocyte retrieval. A total of 44 patients (group A) had 50 retrievals under epidural anesthesia, and 104 patients (group B, control group) 112 retrievals under intravenous sedation (propofol) with mask-assisted ventilation (nitrous oxide).

RESULTS:

In group A satisfactory anesthesia was achieved in 49 of the 50 cases (98%); one patient required additional intravenous administration of propofol owing to extreme anxiety. No complications were observed. Adversely, in group B nausea was observed in 16 cases (14%) and nausea and vomiting in 7 cases (6%). In group A the fertilization, cleavage and pregnancy rates were 67.2%, 92% and 20% respectively, while in group B the rates were 69.3%, 93% and 19.6% respectively; the differences are not statistically significant.

CONCLUSIONS:

Epidural anesthesia is an effective method for transvaginal oocyte retrieval but does not improve the treatment outcome as compared to an intravenous sedation with mask-assisted ventilation using propofol and nitrous oxide.

PMID:
8520183
[PubMed - indexed for MEDLINE]
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