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    J Neurol Sci. 1993 May;116(1):47-51.

    Occurrence of primary biliary cirrhosis, CREST syndrome and Sjögren's syndrome in a patient with HTLV-I-associated myelopathy.

    Kuroda Y, Fukuoka M, Endo C, Matsui M, Kurohara K, Kakigi R, Tokunaga O.

    Department of Internal Medicine (Section of Neurology), Saga Medical School, Japan.

    We report the occurrence of three autoimmune diseases (primary biliary cirrhosis, CREST syndrome and Sjögren's syndrome) in a patient with HTLV-I-associated myelopathy (HAM). The patient had the depressed cell-mediated immune responses but the infiltration of CD8-T cells was found in the cerebrospinal fluid and liver. The clinical and immunological features of this case are similar to those of chronic graft-versus-host disease.

    PMID: 8509804 [PubMed - indexed for MEDLINE]

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