1. This study shows that Reality Orientation (RO) and Validation Therapy have no significant impact on mental status, level of depression, or functional status. 2. Gerontological nurses, administrators, specialists, and practitioners must carefully evaluate and compare all relevant research studies on therapies before implementing therapies in long-term care settings. 3. Gerontological nurse researchers and staff must be aware of the difficulties arising in long-term research: sampling difficulties, patients' behavioral and physical factors, and environmental, staff, and financial resources.