Expression of mRNA for the GATA-binding proteins i...[Blood. 1993]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Blood. 1993 Jun 15;81(12):3234-41. Links

Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription.

Zon LI, Yamaguchi Y, Yee K, Albee EA, Kimura A, Bennett JC, Orkin SH, Ackerman SJ.

Division of Hematology, Children's Hospital, Boston, MA 02115.

The expression of the hematopoietic transcription factors GATA-1, GATA-2, and GATA-3 was studied in eosinophils and basophils. Eosinophils express mRNA for GATA-1, GATA-2, and GATA-3. Basophils express GATA-2 and GATA-3. Treatment of HL-60 eosinophilic sublines with either interleukin-5 or butyric acid increased the expression of GATA-1 mRNA concomitant with the expression of eosinophil-specific genes, whereas levels of GATA-2 mRNA remained relatively constant. The presence of mRNA for these proteins in eosinophils and basophils suggests that gene transcription in these lineages may be regulated by GATA-binding proteins.

PMID: 8507862 [PubMed - indexed for MEDLINE]

Megakaryocytic differentiation induced in 416B myeloid cells by GATA-2 and GATA-3 transgenes or 5-azacytidine is tightly coupled to GATA-1 expression.
Blood. 1993 Sep 1; 82(5):1493-501.

[Blood. 1993]
C/EBPbeta and GATA-1 synergistically regulate activity of the eosinophil granule major basic protein promoter: implication for C/EBPbeta activity in eosinophil gene expression.
Blood. 1999 Aug 15; 94(4):1429-39.

[Blood. 1999]
Mechanisms of transcription in eosinophils: GATA-1, but not GATA-2, transactivates the promoter of the eosinophil granule major basic protein gene.
Blood. 1998 May 1; 91(9):3447-58.

[Blood. 1998]
Review[The trend of molecular biology study on eosinophils]
Nippon Rinsho. 1993 Mar; 51(3):741-6.

[Nippon Rinsho. 1993]
ReviewRegulation of GATA gene expression during vertebrate development.
Semin Cell Dev Biol. 2005 Feb; 16(1):71-81. Epub 2004 Dec 10.

[Semin Cell Dev Biol. 2005]
» See reviews... | » See all...

Cited by 25 PubMed Central articles

Serotonergic transcription of human FEV reveals direct GATA factor interactions and fate of Pet-1-deficient serotonin neuron precursors.
Krueger KC, Deneris ES. J Neurosci. 2008 Nov 26; 28(48):12748-58.

[J Neurosci. 2008]
Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood.
Arshad SH, Karmaus W, Kurukulaaratchy R, Sadeghnejad A, Huebner M, Ewart S. Br J Dermatol. 2008 Jun; 158(6):1315-22. Epub 2008 Apr 10.

[Br J Dermatol. 2008]
Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage.
Cantor AB, Iwasaki H, Arinobu Y, Moran TB, Shigematsu H, Sullivan MR, Akashi K, Orkin SH. J Exp Med. 2008 Mar 17; 205(3):611-24. Epub 2008 Feb 25.

[J Exp Med. 2008]
» See all...

Recent Activity

Clear Turn Off Turn On

Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: poten...Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription.

Related articles

Cited by 25 PubMed Central articles

Recent Activity